• Home
  • Browse
    • Current Issue
    • By Issue
    • By Author
    • By Subject
    • Author Index
    • Keyword Index
  • Journal Info
    • About Journal
    • Aims and Scope
    • Editorial Board
    • Publication Ethics
    • Peer Review Process
  • Guide for Authors
  • Submit Manuscript
  • Reviewers
  • Contact Us
 
  • Login
  • Register
Home Articles List Article Information
  • Save Records
  • |
  • Printable Version
  • |
  • Recommend
  • |
  • How to cite Export to
    RIS EndNote BibTeX APA MLA Harvard Vancouver
  • |
  • Share Share
    CiteULike Mendeley Facebook Google LinkedIn Twitter
Ain Shams Journal of Forensic Medicine and Clinical Toxicology
arrow Articles in Press
arrow Current Issue
Journal Archive
Volume Volume 39 (2022)
Volume Volume 38 (2022)
Volume Volume 37 (2021)
Issue Issue 2
Volume Volume 36 (2021)
Volume Volume 35 (2020)
Volume Volume 34 (2020)
Volume Volume 33 (2019)
Volume Volume 32 (2019)
Volume Volume 31 (2018)
Volume Volume 30 (2018)
Volume Volume 29 (2017)
Volume Volume 28 (2017)
Volume Volume 27 (2016)
Volume Volume 26 (2016)
Volume Volume 25 (2015)
Volume Volume 24 (2015)
Volume Volume 23 (2014)
Volume Volume 22 (2014)
Volume Volume 21 (2013)
Volume Volume 20 (2013)
Volume Volume 19 (2012)
Mahmoud, E., Abdel Salam, M., Halawa, H., Hafez, R. (2021). Red cell distribution width as a predictor of severity and outcome of acute organophosphorus poisoned cases admitted to Poison Control Center Ain Shams University Hospitals (A prospective study). Ain Shams Journal of Forensic Medicine and Clinical Toxicology, 37(2), 26-33. doi: 10.21608/ajfm.2021.175380
Ehdaa Mahmoud; Manal Abdel Salam; Heba Halawa; Rabab Hafez. "Red cell distribution width as a predictor of severity and outcome of acute organophosphorus poisoned cases admitted to Poison Control Center Ain Shams University Hospitals (A prospective study)". Ain Shams Journal of Forensic Medicine and Clinical Toxicology, 37, 2, 2021, 26-33. doi: 10.21608/ajfm.2021.175380
Mahmoud, E., Abdel Salam, M., Halawa, H., Hafez, R. (2021). 'Red cell distribution width as a predictor of severity and outcome of acute organophosphorus poisoned cases admitted to Poison Control Center Ain Shams University Hospitals (A prospective study)', Ain Shams Journal of Forensic Medicine and Clinical Toxicology, 37(2), pp. 26-33. doi: 10.21608/ajfm.2021.175380
Mahmoud, E., Abdel Salam, M., Halawa, H., Hafez, R. Red cell distribution width as a predictor of severity and outcome of acute organophosphorus poisoned cases admitted to Poison Control Center Ain Shams University Hospitals (A prospective study). Ain Shams Journal of Forensic Medicine and Clinical Toxicology, 2021; 37(2): 26-33. doi: 10.21608/ajfm.2021.175380

Red cell distribution width as a predictor of severity and outcome of acute organophosphorus poisoned cases admitted to Poison Control Center Ain Shams University Hospitals (A prospective study)

Article 4, Volume 37, Issue 2, July 2021, Page 26-33  XML PDF (652.47 K)
Document Type: Original Article
DOI: 10.21608/ajfm.2021.175380
Authors
Ehdaa Mahmoud1; Manal Abdel Salam1; Heba Halawa1; Rabab Hafez2
1Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine-Ain Shams University, Cairo Egypt.
2Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine-Ain Shams University, Cairo Egypt
Abstract
Background: Organophosphates are highly toxic compounds for human beings. Organophosphate compounds (OPCs) poisoning by unintentional or suicidal ingestion is associated with high morbidity and mortality, particularly in developing countries. Aim of the study: Assessing the prognostic value of red cell distribution width (RDW) and white blood cells (WBCs), hemoglobin and platelet count on severity and outcome in patients with acute organophosphate poisoning in conjunction with clinical signs using the Peradeniya Organophosphorus Poisoning (POP) score. This is in addition to evaluation and comparison between RDW with pseudo choline esterase (PChE) level as early OPCs poisoning predictor. Methods: A prospective cross-sectional study was done on 100 acutely OPCs intoxicated patients admitted to Poison Control Center Ain Shams University Hospitals (PCC-ASUHs) from June 2019 till December 2019. All cases were clinically evaluated. RDW was done on admission and after 24 hours while WBCs, hemoglobin, platelets, PChE level and arterial blood gases (ABG) were estimated immediately after admission prior to treatment. Results: High RDW values indicated poor prognosis. There was a highly significant correlation between RDW values and the need for mechanical ventilation (MV). There was a significant correlation between high WBCs count, severity of OPCs poisoning and the need for MV. Lower mean pH, higher mean PCO2, lower mean HCO3, lower mean PChE levels, and higher mean WBCs count were noted in patients on MV compared to patients without MV. Conclusion: RDW values on admission can be a reliable predictor of severity and outcome in contrast to PChE levels which showed nonsignificant correlation with severity. Additionally, there was a significant correlation between WBCs with the need of MV. RDW on admission can predict the need for mechanical ventilation with sensitivity (58.97%), specificity (83.61%) at cutoff value more than 14.4. RDW on admission had a sensitivity of 75% and specificity of 73.75% with a cut-off value of 14.3 in predicting mortality in patients with OPCs poisoning. Recommendations: RDW is a simple parameter that could be used in assessing the prognosis of acute organophosphorus poisoning. WBCs count could also be used in those patients to predict the need of MV.
Keywords
Red cell distribution width; acute organophosphate poisoning
Statistics
Article View: 188
PDF Download: 152
Home | Glossary | News | Aims and Scope | Sitemap
Top Top

Journal Management System. Designed by NotionWave.